Hole's Essentials of Human Anatomy & Physiology, 10th Edition (Shier)

Chapter 14: Lymphatic System and Immunity

IgE Mediated (Type 1) Hypersensitivity

View the animation below, then complete the quiz to test your knowledge of the concept.

1.		In IgE mediated hypersensitivity, all of the following are needed except
			A)	antigen presenting cell
			B)	B cell
			C)	IgE antibody
			D)	mast cell
			E)	neutrophil
2.		IgE molecules attach to
			A)	mast cells via their variable region
			B)	mast cells by their constant region
			C)	T helper cells by their variable region
			D)	plasma cells by their constant region
3.		Histamine released by mast cells leads to all of the following symptoms except
			A)	capillary dilation
			B)	airway constriction
			C)	high fever
			D)	mucus secretion
			E)	itching
4.		For a hypersensitivity response to occur, two bound IgE molecules on a mast cell must react with a specific antigen.
			A)	True
			B)	False
5.		Activated T helper cells produce cytokines, which stimulate B cells to proliferate and differentiate into plasma cells capable of producing IgE.
			A)	True
			B)	False