1 Identify functions of the lymphatic system.A) Absorption of fats, acid-base balance and defense against disease. B) Fluid balance, absorption of amino acids and defense against disease. C) Fluid balance, absorption of fats and defense against disease. D) Transport of nutrients, acid-base balance and fluid balance. 2 The lymphatic ducts that direct lymph into blood circulation are called the _________ duct and the ________ duct.A) anterior lymphatic, abdominopelvic B) left lymphatic, subclavian C) right lymphatic, thoracic D) subclavian, thoracic 3 Lymphatic fluid is ultimately drained into:A) arteries B) blood capillaries C) tissue fluid D) veins 4 Describe the flow of lymph beginning with lymph formation.A) lymphatic capillaries – tissue fluid – lymphatic ducts – lymphatic vessels - veins B) tissue fluid - lymphatic capillaries – lymphatic vessels – lymphatic ducts - veins C) tissue fluid – lymphatic capillaries – lymphatic ducts – lymphatic veins - veins D) lymphatic capillaries – veins – tissue fluid – lymphatic ducts – lymphatic veins 5 The structure of the larger lymphatic vessels is similar to the structure of cardiovascularA) arteries B) arterioles C) veins D) venules 6 The ability of the body to react to antigens isA) edema. B) inflammation. C) homeostasis. D) immunity. 7 Identify primary lymphatic organs.A) spleen and red bone marrow B) red bone marrow and thymus C) spleen and thymus gland D) lymph nodes and spleen 8 Primary lymphatic organs serve as the site for:A) antibody formation B) lymph formation C) lymphocytes to encounter and bind to antigens D) lymphocyte formation and maturation 9 B lymphocytes are produced in the ______ and mature in the ______.A) bone marrow; bone marrow B) bone marrow; thymus gland C) lymph nodes; thymus gland D) thymus gland; spleen 10 T lymphocytes are produced in the ______ and mature in the ______.A) bone marrow; bone marrow B) bone marrow; thymus gland C) lymph nodes; thymus gland D) thymus gland; spleen 11 The thymus gland is located within the:A) abdominal cavity, inferior to the liver. B) abdominal cavity, posterior to the stomach C) thoracic cavity, inferior to the heart D) thoracic cavity, between the trachea and the sternum 12 Secondary lymphatic organs serve as the site for:A) antibody formation B) lymph formation C) lymphocytes to encounter and bind to antigens D) lymphocyte formation and maturation 13 Which of the following is NOT true of red bone marrow structure and function?A) All adult bones have active red bone marrow. B) Red and white blood cells and platelets are formed in the red bone marrow. C) Location where B lymphocytes mature. D) Made of reticular tissue. 14 Identify examples of secondary lymphatic structures.A) Bone marrow, lymph nodes, spleen and tonsils. B) Bone marrow, lymph nodes, spleen and thymus gland. C) Lymph nodes, spleen and tonsils D) Lymph nodes, spleen and thymus gland. 15 Thymosins are secreted by the _____ and aid in ______.A) spleen; maturation of B cells B) spleen; maturation of T cells C) thymus gland; maturation of B cells D) thymus gland; maturation of T cells 16 Lymph is filtered by the:A) bone marrow B) kidneys C) lymph nodes D) spleen 17 Identify the lymphatic structure that contains white and red pulp, filters blood and removes worn-out red blood cells.A) Bone marrow B) Lymph nodes C) Spleen D) Thymus gland 18 In order to react to pathogens and remove worn-out red blood cells, the spleen has an abundance of:A) basophils and lymphocytes B) lymphocytes and macrophage C) macrophage and red blood cells D) red blood cells and platelets 19 Within a lymph node, B lymphocytes are located within the ____ of the lymph node and T lymphocytes and macrophage are located within the _____ of the lymph node.A) nodules; nodules B) nodules; sinuses C) sinuses; sinuses D) sinuses; nodules 20 Identify the three specific tonsils.A) Adenoids, pharyngeal and palatine tonsils B) Lingual, palatine and pharyngeal tonsils C) Lingual, palatine and salivary tonsils D) Maxillary, palatine and pharyngeal tonsils 21 Non-specific defense mechanisms are effective against _____ type(s) of infectious agent(s) and specific defense mechanisms are effective against ______ type(s) of infectious agent(s).A) many; many B) many; one C) one; one D) one: many 22 Identify examples of nonspecific defenses.A) Antibody-antigen reaction, complement, interferon and inflammation. B) Antibody-antigen reaction, chemical barriers, complement and inflammation. C) Chemical barriers, complement, interferon and inflammation. D) Cell mediated immunity, complement, interferon and inflammation. 23 Which of the following is NOT a physical barrier that prevents infection?A) intact skin B) mucous membranes C) hydrochloric acid of the stomach D) ciliated cells 24 Which of the following is NOT a chemical barrier that prevents infection?A) normal body flora B) mucous membranes C) lysozyme of tears, perspiration, and saliva D) oily skin secretions 25 Identify the outward signs of inflammation that is a result of the dilation of blood vessels.A) Heat and redness B) Heat and pain C) Redness and swelling D) Swelling and pain 26 Identify the outward signs of inflammation that results from increased capillary permeability.A) Heat and redness B) Heat and pain C) Redness and swelling D) Swelling and pain 27 Place the events of inflammation in chronological order. Clotting and swelling walls off the injured area from the rest of the body. Fluid and clotting factors escape into tissues. Release of histamine leads to dilation of blood vessels. Macrophage phagocytize pathogens and stimulate immune responses. Monocytes and neutrophils migrate into injured tissue.A) 1-2-3-5-4 B) 1-3-2-4-5 C) 3-2-1-5-4 D) 3-2-1-4-5 28 Identify the outward signs of inflammation.A) Heat, pain, redness and swelling B) Heat, itchyness, redness and swelling C) Heat, itchiness, pain and swelling D) Itchyness, pain, redness and swelling 29 Identify the nonspecific defense mechanism that amplifies the inflammatory response and increases the likelihood of phagocytosis by binding to the surface of pathogens.A) Antibodies B) Complement proteins C) Histamine D) Interferon 30 The development of holes in bacterial plasma membranes is caused byA) antibodies B) complement proteins C) histamine D) interferon 31 Proteins produced by virus-infected cells that protect non-infected cells are:A) mast B) histamine C) NK cells D) interferon 32 The chemical produced by injured cells and mast cells that promotes inflammation is:A) complement B) histamine C) lysozymes D) interferon 33 Identify the two types of specific defense mechanisms.A) Antibody-mediated immunity and cell-mediated immunity B) Antibody-mediated immunity and inflammation C) Complement and cell mediated immunity D) Inflammation and complement 34 The bodies first line of defense include:A) Complement, chemical barriers and mechanical barriers. B) Chemical barriers, inflammation and Natural killer cells C) Chemical barriers, mechanical barriers, and normal flora D) Inflammation, natural killer cells and normal flora 35 Identify the cells responsible for specific immunity.A) B lymphocytes and neutrophils. B) T lymphocytes and monocytes. C) B lymphocytes and T lymphocytes. D) Neutrophils and phagocytes. 36 Defense by B cells is known asA) humoral immunity. B) cell mediated immunity. C) antibody mediated immunity. D) Both A and B E) Both A and C 37 B cell clones formA) memory B cells. B) antibodies. C) plasma cells. D) memory B cells and plasma cell 38 Once an infection has passed, plasma cells die due toA) apoptosis. B) NK cells. C) phagocytosis. D) interferon. 39 Antibodies are produced byA) memory B cells B) plasma cells C) helper T cells D) killer T cells 40 Most antibodies belong to the class:A) IgA B) IgD C) IgE D) IgG 41 Identify the class of antibodies that cause allergies.A) IgA B) IgD C) IgE D) IgG 42 Which antibody class is correctly matched with where it is found?A) IgG - on basophils and mast cells B) IgD - on immature B cells C) IgA - secretions such as milk and saliva D) IgE - in circulation 43 Identify the class of antibody that attacks parasitic infections.A) IgA B) IgE C) IgG D) IgM 44 Identify the class of antibody found in saliva and breast milk.A) IgA B) IgD C) IgE D) IgM 45 Identify the class of antibody that crosses the placenta.A) IgA B) IgD C) IgE D) IgG 46 Identify the class of antibody that is formed first in a new infection.A) IgA B) IgD C) IgG D) IgM 47 An antigen-antibody complex mayA) activate complement. B) attract phagocytotic cells. C) neutralize toxins. D) All of the above are correct. 48 When an antigen-presenting cell (APC) presents an antigen to a T cell, it mustA) link to a B cell first. B) join with an antibody. C) join with complement. D) link to a major histocompatibility complex protein on the cell membrane. 49 Which of the following is NOT true of T cell activation?A) An activated T cell produces cytokines. B) An activated T cell undergoes clonal selection. C) An activated T cell produces antibodies. D) T cells are activated by antigen presentation. 50 Identify the function of perforins.A) Activate complement B) Bind to antigens C) Drills holes into plasma membranes D) Stimulate inflammation 51 Cytotoxic T calls are also called _____ leukocytes and helper T cells are also called _____ leukocytes.A) CD4; CD8 B) CD4; NK C) CD8; CD4 D) NK; CD8 52 Identify the specific defense cell that destroys virus-infected cells and cancerous cells.A) B lymphocytes B) Cytotoxic T cells C) Helper T cells D) NK cells 53 Perforins are secreted by:A) B lymphocytes B) cytotoxic T cells C) helper T cells D) macrophage 54 Cell-mediated immunity occurs due to the actions of:A) B lymphocytes B) cytotoxic T cells C) monocytes D) plasma cells 55 HIV, the virus that causes AIDS, infects:A) B lymphocytes B) cytotoxic T cells C) helper T cells D) neutrophils 56 What will stimulate active immunity?A) infection with a pathogen or injection of an antiserum B) antiserum or vaccination with an antigen C) infection with a pathogen or vaccination with an antigen D) only infection with a pathogen 57 Maternal antibodies crossing the placenta to the fetus is an example of:A) artificial active immunity B) artificial passive immunity C) natural active immunity D) natural passive immunity 58 Jimmy got the chicken pox when he was six years old. What type of immunity does he have?A) natural active B) artificial active C) natural passive D) Artificial passive 59 Jimmy's baby sister received the immunization for chicken pox. What type of immunity does she have?A) natural active B) artificial active C) natural passive D) artificial passive 60 Billy was bitten by a rabid dog and had to receive the rabies serum vaccine. What type of immunity does he have?A) natural active B) artificial active C) natural passive D) artificial passive 61 A retrovirus has what kind of genetic material?A) r-DNA B) RNA C) d-RNA D) c-DNA 62 A person with a T lymphocyte count between 200 and 499 per cubic mm, swollen lymph nodes, and a recurrent fever would be in the __________ stage of an HIV-1 infection.A) category A B) category B C) category C 63 Antibodies of the same type and produced by plasma cells derived from the same B cell are called what?A) monoclonal antibodies B) anticlonal antibodies C) SARS D) radioactive 64 During an allergic reaction, mast cells releaseA) allergens B) antibodies C) histamine D) interferon 65 Anaphylactic shock is an example of a(n):A) tissue rejection. B) an immediate allergic response. C) B cells aging. D) rheumatoid arthritis. 66 An allergic response such as contact dermatitis is caused byA) IgE. B) memory T cells. C) memory B cells. D) IgM. 67 The amount of antibody present in a blood plasma sample is a(n):A) antigen B) booster C) titer D) vaccine 68 Tissue rejection is due to the action ofA) cytotoxic T cells. B) helper T cells. C) IgE antibodies. D) memory B cells. 69 Which of the following is NOT an autoimmune disease?A) SCID B) myastenia gravis C) multiple sclerosis D) rheumatoid arthritis 70 An exaggerated immune response to substances that do not ordinarily harm the body is a(n):A) allergy B) autoimmune disease C) immune deficiency D) inflammation 71 The elderly have a(n) ______ risk of infection and the elderly's response to vaccines ______.A) decreased; decreases B) decreased; increases C) increased; increases D) increased; decreases