Human Genetics, 10th Edition, (Lewis)

Chapter 22: Genomics

Learning Outcomes


22.1

 

From Genetics to Genomics

1.

  

Explain how linkage studies led to the idea to sequence the human genome.

2.

  

Distinguish between the two approaches used to sequence the human genome.

22.2

 

DNA Sequencing and Genome Synthesis

3.

  

Describe the Sanger method of DNA sequencing.

4.

  

Describe how newer methods of DNA sequencing work.

5.

  

Define synthetic genome.

22.3

 

Ways of Looking at Genomes

6.

  

List questions that comparative genomics can address.

7.

  

Discuss what the analysis of a representative 1 percent of the human genome revealed.

8.

  

Define human microbiome.

22.4

 

Personal Genome Sequencing

9.

  

What types of information can personal genome sequencing provide?

10.

  

What are limitations of the utility of personal genome sequencing?

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